| Lymphocytic hypophysitis with a long latent period before development of a pituitary mass. | |
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MedLine Citation:
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PMID: 15376489 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Lymphocytic hypophysitis is an autoimmune condition that commonly presents in women of childbearing age as hypopituitarism and a sellar mass. CASE REPORT: A 66-year-old woman presented with anterior pituitary dysfunction. Computed tomography imaging revealed a small hypodensity that was not felt to be the cause of the pituitary dysfunction. Eight years later, her vision rapidly deteriorated and MRI showed a pituitary mass lesion causing optic chiasm compression. Histological examination of the partially resected gland revealed evidence of lymphocytic hypophysitis. CONCLUSION: Our patient is an example of the variable presentation and course of lymphocytic hypophysitis. Such a long latent period between the initial presentation of adenohypophysial hypofunction and optic chiasm compression due to an enlarging pituitary mass has not been reported. |
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Authors:
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Rene W G Wong; Teik Chye Ooi; Brien Benoit; David Zackon; Gerard Jansen; Adam Telner |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques Volume: 31 ISSN: 0317-1671 ISO Abbreviation: Can J Neurol Sci Publication Date: 2004 Aug |
Date Detail:
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Created Date: 2004-09-20 Completed Date: 2004-10-18 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0415227 Medline TA: Can J Neurol Sci Country: Canada |
Other Details:
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Languages: eng Pagination: 406-8 Citation Subset: IM |
Affiliation:
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Division of Endocrinology and Metabolism, Ottawa Hospital, University of Ottawa, Canada. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Aged Autoimmune Diseases / immunology*, pathology* Female Humans Inflammation Lymphocytes* Optic Chiasm / pathology Pituitary Diseases / immunology*, pathology* Pituitary Gland / pathology Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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