Document Detail

Lymphocytic hypophysitis and pulmonary sarcoidosis. Report of a case.
MedLine Citation:
PMID:  2014777     Owner:  NLM     Status:  MEDLINE    
Lymphocytic hypophysitis is one of the causes of hypopituitarism in the postpartum period. Some of these patients have been reported to have other organ-specific autoimmune diseases, and the disease is considered to be autoimmune in nature. The authors describe a unique case of lymphocytic hypophysitis in a young woman. She had hemianopia that developed three days after delivery. Computed tomography scans revealed an intrasellar mass lesion. Secretions of adrenocorticotropic hormone and growth hormone were decreased. Although no organ-specific autoantibodies were detected in her serum, OKT4-positive helper T lymphocytes were increased in peripheral blood. Pituitary biopsy at craniotomy showed typical features of lymphocytic hypophysitis. Pulmonary and eye sarcoidosis developed 11 months after the delivery. This is, to the authors' knowledge, the first case of lymphocytic hypophysitis associated with sarcoidosis in other organs.
H Hayashi; K Yamada; T Kuroki; M Katayama; M Shigemori; S Kuramoto; K Nonaka
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  American journal of clinical pathology     Volume:  95     ISSN:  0002-9173     ISO Abbreviation:  Am. J. Clin. Pathol.     Publication Date:  1991 Apr 
Date Detail:
Created Date:  1991-05-10     Completed Date:  1991-05-10     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0370470     Medline TA:  Am J Clin Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  506-11     Citation Subset:  AIM; IM    
Department of Medicine, Kurume University School of Medicine, Fukuoka, Japan.
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MeSH Terms
Eye Diseases / complications,  pathology
Hypopituitarism / etiology,  pathology
Lung Diseases / complications*,  pathology
Pituitary Diseases / complications*,  pathology
Pituitary Gland / pathology,  radiography
Pregnancy Complications / etiology,  pathology
Sarcoidosis / complications*,  pathology
T-Lymphocytes / pathology
Tomography, X-Ray Computed

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