Document Detail


Lymphocytic hypophysitis in children: a novel presentation and literature review.
MedLine Citation:
PMID:  21212455     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Lymphocytic hypophysitis, an autoimmune mediated chronic inflammation of the pituitary gland, is uncommon in children.(1) The usual presentation is with symptoms secondary to pressure from the enlargement of the gland itself and or impairment of pituitary hormones of varying degrees, in conjunction with a sellar mass.( 2,3) In 80% of cases, partial or panhypopituitarism is present with approximately 75% of cases having multiple hormonal deficiencies.(2) We report the case of a prepubertal female who presented with cyclical vomiting, as her initial symptom of lymphocytic hypophysitis which resolved promptly after pituitary biopsy. This case suggests that cyclical vomiting can be a symptom associated with lymphocytic hypophysitis. Therefore, it should be considered in the differential diagnosis of any child presenting with cyclical vomiting.
Authors:
Arun A Kalra; Rosario Maria S Riel-Romero; Eduardo Gonzalez-Toledo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of child neurology     Volume:  26     ISSN:  1708-8283     ISO Abbreviation:  J. Child Neurol.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  87-94     Citation Subset:  IM    
Affiliation:
Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, LA, USA. akalra@lsuhsc.edu
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