| Lymphocytic adenohypophysitis and adrenalitis in a dog with adrenal and thyroid atrophy. | |
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MedLine Citation:
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PMID: 20807820 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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A 4.5-year-old spayed female Great Pyrenees with hypothyroidism and hypoadrenocorticism had a slightly enlarged pituitary gland and bilaterally atrophic adrenal and thyroid glands. Lymphocytic adenohypophysitis and adrenalitis were found in which B lymphocytes and plasma cells dominated the adenohypophysitis but T cells dominated the adrenalitis. The thyroid gland had extensive follicular atrophy and collapse. The combination of primary hypothyroidism and hypoadrenocorticism resembles type II autoimmune polyendocrine syndrome or Schmidt syndrome in humans. Adenohypophysitis is rare in dogs and not reported in polyendocrine disease in animals. |
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Authors:
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H A Adissu; A Hamel-Jolette; R A Foster |
Publication Detail:
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Type: Journal Article Date: 2010-08-31 |
Journal Detail:
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Title: Veterinary pathology Volume: 47 ISSN: 1544-2217 ISO Abbreviation: Vet. Pathol. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0312020 Medline TA: Vet Pathol Country: United States |
Other Details:
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Languages: eng Pagination: 1082-5 Citation Subset: IM |
Affiliation:
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Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, N1G 2W1, Canada. hadissu@uoguelph.ca |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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