| Lymphocyte transformation test in patients with American leishmaniasis. | |
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MedLine Citation:
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PMID: 3972147 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To determine the correlation between the lymphocyte transformation test (LTT) with phytohemagglutinin (PHA) and the clinical forms of American leishmaniasis (AL), duration of the disease and reaction to leishmanin, the authors studied 12 patients and compared them to 25 unaffected individuals. The ulcerated cutaneous form of the disease was observed in 4 patients, the ulcero-nodular lymphangitic form in 1, the mucous cutaneous form with destruction of the nose in 6, and the verrucous form in 1. General patient condition was satisfactory and the Montenegro reaction macroscopically positive with infiltrations of 5-15 mm in diameter. The results revealed no evidence of immunodeficiency among patients. No correlation was observed between clinical forms, duration of the disease and Montenegro reaction and LTT results. LTT with PHA does not appear to be an adequate indicator of the cell immune system in AL cases. |
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Authors:
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P M Pagnano; J C da Costa; L M Bechelli |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Dermatologica Volume: 170 ISSN: 0011-9075 ISO Abbreviation: Dermatologica Publication Date: 1985 |
Date Detail:
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Created Date: 1985-04-08 Completed Date: 1985-04-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0211607 Medline TA: Dermatologica Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 22-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Child Female Humans Immunity, Cellular Leishmaniasis / immunology* Lymphocyte Activation* Male Middle Aged Phytohemagglutinins / pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Phytohemagglutinins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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