| Lymphocyte transformation test in adult patients with minimal change nephrotic syndrome. | |
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MedLine Citation:
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PMID: 8091126 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The lymphocyte transformation test was used to evaluate the cellular immune response in 31 adult patients with MCNS in comparison with 30 normal control and 49 patient (CRF, FSGN, MGN) control groups. The results showed that the stimulation indices of the lymphocytes in MCNS group were significantly lower than those of the normal control and patient control groups with the exception of CRF group. In cross studies, lymphocytes obtained from normal individuals were incubated in homologous serum obtained from MCNS patients in relapse, and lymphocytes from MCNS patients in relapse were incubated in normal homologous AB serum. In both circumstances there was a depressed lymphocyte function which indicates that there is a defect in lymphocyte itself as well as a serum inhibitory factor(s) during the active stage of the MCNS. This depressed cellular immune response returned to normal level during remission of the patients with MCNS. |
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Authors:
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Y H al-Azzawi; N G al-Tawil; I A al-Shamaa |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Scandinavian journal of immunology Volume: 40 ISSN: 0300-9475 ISO Abbreviation: Scand. J. Immunol. Publication Date: 1994 Sep |
Date Detail:
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Created Date: 1994-10-14 Completed Date: 1994-10-14 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0323767 Medline TA: Scand J Immunol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 277-80 Citation Subset: IM |
Affiliation:
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Department of Microbiology, College of Medicine, University of Baghdad, Iraq. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Cells, Cultured Female Humans Lymphocyte Activation* Male Nephrosis, Lipoid / immunology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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