| Lymphocyte subset reconstitution in pediatric liver recipients induced with steroid-free rabbit anti-human thymocyte globulin. | |
MedLine Citation:
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PMID: 18972618 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Multiple measurements of lymphocyte subsets in 91 children treated with steroid-free tacrolimus, and rabbit anti-human thymocyte globulin induction demonstrate early reconstitution of T-cytotoxic cells, and gradual reconstitution of all other subsets, which is complete after one yr. Rejection-prone children demonstrate significantly higher counts of lymphocytes and all subsets prior to liver transplantation, and may exemplify one basis for enhanced baseline immunocompetence. |
Authors:
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Anjan Talukdar; Chethan AshokKumar; Jennifer Farrar; Patrick Wilson; Arun Janakiramanan; Mary Tregaskes; Rakesh Sindhi |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Pediatric transplantation Volume: 12 ISSN: 1399-3046 ISO Abbreviation: Pediatr Transplant Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-10-29 Completed Date: 2009-03-26 Revised Date: 2013-06-05 |
Medline Journal Info:
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Nlm Unique ID: 9802574 Medline TA: Pediatr Transplant Country: Denmark |
Other Details:
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Languages: eng Pagination: 804-8 Citation Subset: IM |
Affiliation:
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Pediatric Transplantation Laboratory, Hillman Center for Pediatric Transplantation, Childrens Hospital of Pgh and the University of Pittsburgh, Pittsburgh, PA, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Animals Antilymphocyte Serum / metabolism* Child Child, Preschool Female Humans Infant Liver Diseases / blood*, therapy* Liver Transplantation / methods* Lymphocyte Subsets / cytology* Male Rabbits Steroids / metabolism* T-Lymphocytes, Cytotoxic / metabolism Tacrolimus / administration & dosage |
| Grant Support | |
ID/Acronym/Agency:
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5R01AI49156-05/AI/NIAID NIH HHS; R01 AI049156-01A1/AI/NIAID NIH HHS; R01 AI073895-01/AI/NIAID NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Antilymphocyte Serum; 0/Steroids; 109581-93-3/Tacrolimus |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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