Document Detail

Lymphocyte populations and responses to mitogens in infants of diabetic mothers.
MedLine Citation:
PMID:  6212685     Owner:  NLM     Status:  MEDLINE    
A group of 10 infants of diabetic mothers, born prematurely by Caesarian section was compared to an age-matched group of premature controls and to full-term newborns. There was no difference between the three groups in terms of lymphocyte populations at birth. The percentage of T-cells in the three groups was significantly lower than in adults but reached adult levels at 1 month of age. The mitogenic responses in infants of diabetic mothers was found significantly higher than in the two control groups at birth and remained so at one month of age. The suppressor T-cell activity was decreased in infants of diabetic mothers as compared with controls.
A El Mohandes; J L Touraine; F Touraine; A S Shukry; B Salle
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical & laboratory immunology     Volume:  8     ISSN:  0141-2760     ISO Abbreviation:  J Clin Lab Immunol     Publication Date:  1982 May 
Date Detail:
Created Date:  1982-09-24     Completed Date:  1982-09-24     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7808987     Medline TA:  J Clin Lab Immunol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  25-9     Citation Subset:  IM    
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MeSH Terms
B-Lymphocytes / immunology
Cytotoxicity Tests, Immunologic
Diabetes Mellitus, Type 1 / immunology*
Fetal Blood / cytology
Immunity, Cellular
Infant, Newborn*
Infant, Premature
Lymphocyte Activation
Lymphocytes / classification*,  immunology
Mitogens / pharmacology*
Rosette Formation
T-Lymphocytes / immunology
T-Lymphocytes, Regulatory / immunology
Reg. No./Substance:

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