| Lymphocyte-depleted Hodgkin Lymphoma Complicating Hemophagocytic Lymphohistiocytosis as an Initial Manifestation: A Case Report and Review of the Literature. | |
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MedLine Citation:
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PMID: 23124152 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Hemophagocytic lymphohistocytosis (HLH) is commonly associated with infectious diseases or T/NK cell-lymphoma; however that with Hodgkin lymphoma (HL) was rarely reported. Herein, we describe a young male diagnosed with lymphocyte-depleted HL (LD-HL) complicated by HLH as an initial manifestation. He was given high-dose steroid therapy plus recombinant thrombomodulin, and subsequent ABVd (doxorubicin, bleomycin, vinblastine, dacarbazine) treatment. In spite of the achievement of a partial remission treated with one cycle of ABVd, he relapsed after 3 cycles. To our knowledge, the present case is very rare, and more intensive treatment might be needed for the long-term control of HLH-complicated HL. |
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Authors:
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Masao Hagihara; Morihiro Inoue; Jian Hua; Yasunobu Iwaki |
Publication Detail:
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Type: Journal Article Date: 2012-11-01 |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 51 ISSN: 1349-7235 ISO Abbreviation: Intern. Med. Publication Date: 2012 |
Date Detail:
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Created Date: 2012-11-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: Japan |
Other Details:
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Languages: eng Pagination: 3067-72 Citation Subset: IM |
Affiliation:
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Department of Hematology, Eiju General Hospital, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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