| Lymphatic vessels: pressure- and flow-dependent regulatory reactions. | |
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MedLine Citation:
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PMID: 18519963 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This chapter discusses the current status of knowledge on basic pressure/stretch- and flow/shear-dependent regulatory reactions of contracting lymphangions in lymphatic vessels. The balance of passive and active lymph pumps is discussed; the data on pressure measurements in different lymphatic nets of several species are provided. The characteristics of typical changes in lymphatic contractility to the increases in transmural pressures are described and discussed, as is the role of pre-existing distension in initiation of lymphatic contractions. The up-to-date status of knowledge on flow-dependent adaptive reactions of contracting lymphangions is provided with detailed characterization of the influences of imposed and contraction-generated flows on lymphatic contractility. The interaction between extrinsic and intrinsic flows in regulation of lymphatic contractility is considered. |
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Authors:
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Anatoliy A Gashev |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Annals of the New York Academy of Sciences Volume: 1131 ISSN: 0077-8923 ISO Abbreviation: Ann. N. Y. Acad. Sci. Publication Date: 2008 |
Date Detail:
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Created Date: 2008-06-03 Completed Date: 2008-07-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7506858 Medline TA: Ann N Y Acad Sci Country: United States |
Other Details:
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Languages: eng Pagination: 100-9 Citation Subset: IM |
Affiliation:
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Department of Systems Biology and Translational Medicine, Cardiovascular Research Institute, Division of Lymphatic Biology, College of Medicine, Texas A&M Health Science Center, 702 SW H.K. Dodgen Loop, Temple, TX 76504, USA. gashev@tamu.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Homeostasis* Humans Lymphatic Vessels / physiology* Pressure Rheology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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