Document Detail


Lymphatic absorption of nonvolatile oxidation products of heated oils in the rat.
MedLine Citation:
PMID:  7219085     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The lymphatic absorption of nonvolatile oxidation products (NVOP) formed during heating of fats was studied. Heated colza or soybean oils or synthetic triglycerides containing a definite aromatic or alicyclic fatty acid were fed to thoracic duct-cannulated rats. Tritium-labeled triolein was added to each dietary fat, as an internal standard, in order to calculate the percentage of lymphatic absorption of the ingested NVOP. Results show that 4% of the total polymeric acids, 53% of the total oxidized monomeric acids and 96% of the total cyclic monomeric acids were recovered in the lymphatic lipids. Gas liquid and quantitative thin layer chromatography of these 3 classes indicated that, within a NVOP class, the various constituents did not present the same absorption rate. The lymphatic absorptions of individual oxidized monomers were between 25 and 93%. Concerning the polymer fraction, the lymphatic recoveries were 1% (nonpolar dimers), 6.8% (polar dimers) and 12% (polar oligomers). Aromatic acids were absorbed to a lesser degree (50-60%) than cyclohexenic acids (91-98%).
Authors:
N Combe; M J Constantin; B Entressangles
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Lipids     Volume:  16     ISSN:  0024-4201     ISO Abbreviation:  Lipids     Publication Date:  1981 Jan 
Date Detail:
Created Date:  1981-06-25     Completed Date:  1981-06-25     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0060450     Medline TA:  Lipids     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  8-14     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cyclohexenes
Dietary Fats / metabolism*
Fatty Acids / metabolism*
Hot Temperature
Intestinal Absorption
Isomerism
Lymph / metabolism*
Male
Oils / metabolism
Oxidation-Reduction
Rats
Structure-Activity Relationship
Triglycerides / metabolism*
Volatilization
Chemical
Reg. No./Substance:
0/Cyclohexenes; 0/Dietary Fats; 0/Fatty Acids; 0/Oils; 0/Triglycerides; 75779-89-4/9-(2'-propylcyclohex-4'-en-1'-yl)nonanoic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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