Document Detail


Lymphangiogenesis: Molecular mechanisms and future promise.
MedLine Citation:
PMID:  20178740     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The growth of lymphatic vessels (lymphangiogenesis) is actively involved in a number of pathological processes including tissue inflammation and tumor dissemination but is insufficient in patients suffering from lymphedema, a debilitating condition characterized by chronic tissue edema and impaired immunity. The recent explosion of knowledge on the molecular mechanisms governing lymphangiogenesis provides new possibilities to treat these diseases.
Authors:
Tuomas Tammela; Kari Alitalo
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cell     Volume:  140     ISSN:  1097-4172     ISO Abbreviation:  Cell     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-24     Completed Date:  2010-03-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413066     Medline TA:  Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  460-76     Citation Subset:  IM    
Copyright Information:
2010 Elsevier Inc. All rights reserved.
Affiliation:
Molecular/Cancer Biology Laboratory and Haartman Institute, University of Helsinki, Finland.
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MeSH Terms
Descriptor/Qualifier:
Animals
Endothelial Cells / physiology
Humans
Inflammation / physiopathology
Lymphangiogenesis* / drug effects
Lymphatic Vessels / physiology,  physiopathology
Neoplasms / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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