| Lymph node management in clinically node-negative patients with papillary thyroid carcinoma. | |
| | |
MedLine Citation:
|
PMID: 20584589 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
AIMS: Systematic lymph node dissection in patients with papillary thyroid carcinoma (PTC) remains controversial. The objective of this study was to study the pattern of lymph node spread in patients with PTC clinically node-negative and then to propose a lymph node management strategy. METHODS: We retrospectively reviewed the records of patients who had undergone total thyroidectomy and a systematic central neck dissection (CND) and lateral neck dissection. Ninety patients with PTC without lymph nodes metastases (LNM) detected on preoperative palpation and ultrasonographic examination were included. RESULTS: Forty-one patients (45.5%) had LNM. Twenty-eight patients (31%) had a central and a lateral involvement. Thirteen patients (14.5%) had only a central involvement. All the patients without LNM in the central compartment were also free in the lateral compartment. There was no correlation between LNM status and TNM staging. The largest LNM in the central compartment was smaller than or equal to 5mm in 66% of the cases, and that could explain the lack of sensitivity of the preoperative ultrasonographic examination. CONCLUSION: CND could be considered at preoperative or intraoperative diagnosis of PTC whereas lateral neck dissection should be performed only in patients with preoperative suspected and/or intraoperatively proven LNM. Systematic CND allows an objective evaluation of lymph node status in this central cervical area where the LNM are particularly small and difficult to detect preoperatively. |
| | |
Authors:
|
S Vergez; J Sarini; J Percodani; E Serrano; Ph Caron |
Related Documents
:
|
16537089 - Retroperitoneal nodal metastasis in primary and recurrent granulosa cell tumors of the ... 17669909 - Retrospective study of patients with pathologic n1-stage ii non-small cell lung cancer. 9878329 - Prognostic factors and rational approach in the treatment of submucosal cancer of the s... 18982749 - Computer-guided surgery for gastric carcinoma. 1743209 - Unexpected uptake of technetium 99m hexakis-2-methoxy-isobutylisonitrile in giant lymph... 21046499 - A study of the assessment of axillary lymph nodes before surgery for breast cancer usin... 20182809 - Prognostic value of perineural invasion in patients with stage ii colorectal cancer. 11796309 - Antiandrogens in the treatment of priapism. 14998849 - Severe hepatic sinusoidal obstruction associated with oxaliplatin-based chemotherapy in... |
Publication Detail:
|
Type: Journal Article Date: 2010-06-26 |
Journal Detail:
|
Title: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology Volume: 36 ISSN: 1532-2157 ISO Abbreviation: Eur J Surg Oncol Publication Date: 2010 Aug |
Date Detail:
|
Created Date: 2010-07-19 Completed Date: 2010-07-26 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8504356 Medline TA: Eur J Surg Oncol Country: England |
Other Details:
|
Languages: eng Pagination: 777-82 Citation Subset: IM |
Copyright Information:
|
Copyright (c) 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
|
Department of Head and Neck Surgery, University Hospital Rangueil-Larrey, Toulouse, France. vergez.s@chu-toulouse.fr |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Aged, 80 and over Carcinoma, Papillary / secondary*, surgery* Carcinoma, Papillary, Follicular / secondary, surgery Female Humans Lymph Nodes / pathology, surgery Lymphatic Metastasis Male Middle Aged Neck Dissection* / methods Neoplasm Staging Retrospective Studies Thyroid Neoplasms / pathology*, surgery* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Rates of fetal alcohol exposure among newborns in a high-risk obstetric unit.
Next Document: Correlation or coincidence between monocytosis and worsening of psychotic symptoms in veterans with ...