| Lymph node biopsy in the diagnostic and prognostic assessment of patients with HIV infection. | |
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MedLine Citation:
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PMID: 2807838 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirty-three anti-HIV positive patients with persistent generalized lymphadenopathy (PGL) who underwent lymph-node biopsy were studied to assess the diagnostic and prognostic relations existing between clinical, histological and laboratory findings. Patients were also examined for known risk factors, laboratory and bacteriological tests, and mononuclear cell surface marker analysis. 4 histological types were identified according to Ràcz's classification. At biopsy, there were 21 cases of LAS (64%), 6 cases of ARC (18%) and 6 cases of AIDS (18%); a clear prevalence of type 1 was evidenced in LAS/ARC patients, while only type 4 was present in the AIDS group. An ARC type 3 patient developed manifest AIDS within 13 months from biopsy. These results suggest that anti-HIV positive asymptomatic patients with PGL apparently do not require lymph node biopsy, as none of them showed histologic findings suggestive of opportunistic infections, malignant lymphoma or Kaposi's sarcoma. On the contrary, lymph node biopsy can play a diagnostic and prognostic role in anti-HIV negative subjects with PGL, and in ARC and AIDS patients. |
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Authors:
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F Badellino; L Moresco; M Gipponi; F Cafiero; A Perasole; G Pagano; A Alessandrini; G Nicolò |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The Italian journal of surgical sciences / sponsored by Società italiana di chirurgia Volume: 19 ISSN: 0392-3525 ISO Abbreviation: Ital J Surg Sci Publication Date: 1989 |
Date Detail:
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Created Date: 1989-12-05 Completed Date: 1989-12-05 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8213451 Medline TA: Ital J Surg Sci Country: ITALY |
Other Details:
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Languages: eng Pagination: 217-24 Citation Subset: IM; X |
Affiliation:
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Divisione di Oncologia Chirurgica, Istituto Nazionale per la Ricerca sul Cancro, Genova. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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AIDS-Related Complex
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pathology* Acquired Immunodeficiency Syndrome / pathology Adolescent Adult Biopsy Child Child, Preschool Female Follow-Up Studies HIV Infections / pathology* Humans Lymph Nodes / pathology* Male Prognosis Risk Factors |
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