| Lyme meningitis: a one-year follow up controlled study. | |
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MedLine Citation:
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PMID: 10666809 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirty-six patients with Lyme meningitis diagnosed at the Department of Infectious Diseases, University Medical Centre, Ljubljana in 1993 and 1994 were enrolled in a prospective study. All patients had lymphocytic meningitis, negative serum IgM antibody titres to tick-borne encephalitis virus and met at least one of the following four criteria: i) isolation of Borrelia burgdorferi sensu lato from cerebrospinal fluid (2 patients), ii) intrathecal borrelial antibody production (22 patients) iii) seroconversion to borrelial antigens (3 patients) and/or iv) erythema migrans in the period of four months prior to the onset of neurological involvement (21 patients). All patients underwent antibiotic treatment and were followed up for one year. The results of our study revealed that Lyme meningitis frequently occurs without meningeal signs and is often accompanied by additional neurological and/or other manifestations of Lyme borreliosis. During the first year after antibiotic treatment, minor and major manifestations of Lyme borreliosis persisted or occurred for the first time in several patients. They were not infrequent even at the examination performed one year after therapy. |
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Authors:
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J Cimperman; V Maraspin; S Lotric-Furlan; E Ruzić-Sabljić; F Strle |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Wiener klinische Wochenschrift Volume: 111 ISSN: 0043-5325 ISO Abbreviation: Wien. Klin. Wochenschr. Publication Date: 1999 Dec |
Date Detail:
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Created Date: 2000-02-29 Completed Date: 2000-02-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 21620870R Medline TA: Wien Klin Wochenschr Country: AUSTRIA |
Other Details:
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Languages: eng Pagination: 961-3 Citation Subset: IM |
Affiliation:
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Department of Infectious Diseases, University Medical Centre, Ljubljana, Slovenia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Anti-Bacterial Agents / adverse effects, therapeutic use* Antibodies, Bacterial / cerebrospinal fluid Borrelia burgdorferi Group / immunology Female Follow-Up Studies Humans Immunoglobulin G / cerebrospinal fluid Immunoglobulin M / cerebrospinal fluid Lyme Disease / diagnosis, drug therapy*, immunology Male Meningitis, Bacterial / diagnosis, drug therapy*, immunology Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Antibodies, Bacterial; 0/Immunoglobulin G; 0/Immunoglobulin M |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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