Document Detail

Lyme disease: resolution of a serous retinal detachment and chorioretinal folds after antibiotic therapy.
MedLine Citation:
PMID:  25389719     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Ocular manifestations of Lyme disease are uncommon. There has not been a documented case of serous retinal detachment and chorioretinal folds because of Lyme disease that have resolved after only antibiotic treatment.
METHODS (CASE REPORT): A 69-year-old white man with a history of recent tick bites presented with a gradual decrease in visual acuity in the left eye. Initial visual acuity was 3/200 in the left eye. Examination revealed an inferior, serous, macula-off retinal detachment. Chorioretinal folds were also noted. Lyme screening antibody test (enzyme-linked immunosorbent assay) was positive and a confirmatory Western blot was immunoglobulin M negative and immunoglobulin G positive.
RESULTS: Oral amoxicillin (500 mg 3 times daily for 2 weeks) was given followed by intravenous ceftriaxone (2 g daily for 4 weeks). After two weeks of ceftriaxone, fundus examination and ultrasonography showed complete reattachment of the macula and periphery, and only mild residual chorioretinal folds remained on fluorescein angiogram.
CONCLUSION: We suggest that Borrelia burgdorferi infection led to choroidal inflammation with secondary chorioretinal folds and a serous retinal detachment, which resolved with antibiotic therapy alone. This supports the suspicion of an intraocular infection, perhaps involving the choroid, as opposed to a secondary autoimmune reaction.
Hans S Grinager; David A Krason; Timothy W Olsen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Retinal cases & brief reports     Volume:  6     ISSN:  1935-1089     ISO Abbreviation:  Retin Cases Brief Rep     Publication Date:  2012  
Date Detail:
Created Date:  2014-11-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101298744     Medline TA:  Retin Cases Brief Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  232-4     Citation Subset:  -    
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