Document Detail


Luteoma-induced fetal virilization.
MedLine Citation:
PMID:  20149054     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A pregnancy luteoma represents an unusual response of ovarian stromal cells to the altered hormonal levels of pregnancy. It is a distinctive non-neoplastic lesion characterized by solid proliferations of luteinized cells resulting in a tumor-like ovarian enlargement. Most patients are asymptomatic; the ovarian enlargement is usually discovered incidentally at cesarean section or during postpartum tubal ligation. We report a typical case that we found at cesarean section to be associated with a virilized infant who manifested clitoromegaly and labial fusion. We detected an increased level of testosterone in the maternal patient. We concluded that the ovarian luteoma induced the fetal virilization.
Authors:
Hiromi Ugaki; Takayuki Enomoto; Yoshihiro Tokugawa; Tadashi Kimura
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The journal of obstetrics and gynaecology research     Volume:  35     ISSN:  1447-0756     ISO Abbreviation:  J. Obstet. Gynaecol. Res.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2010-02-12     Completed Date:  2010-05-03     Revised Date:  2012-01-19    
Medline Journal Info:
Nlm Unique ID:  9612761     Medline TA:  J Obstet Gynaecol Res     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  991-3     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Osaka University, Graduate School of Medicine, Osaka, Japan. hirohiromimi@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Cesarean Section
Female
Humans
Infant, Newborn
Luteoma / blood,  complications*
Maternal-Fetal Exchange
Ovarian Neoplasms / blood,  complications*
Pregnancy
Pregnancy Complications, Neoplastic / diagnosis
Testosterone / blood
Virilism / blood,  etiology*
Chemical
Reg. No./Substance:
58-22-0/Testosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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