Document Detail

Luteoma-induced fetal virilization.
MedLine Citation:
PMID:  20149054     Owner:  NLM     Status:  MEDLINE    
A pregnancy luteoma represents an unusual response of ovarian stromal cells to the altered hormonal levels of pregnancy. It is a distinctive non-neoplastic lesion characterized by solid proliferations of luteinized cells resulting in a tumor-like ovarian enlargement. Most patients are asymptomatic; the ovarian enlargement is usually discovered incidentally at cesarean section or during postpartum tubal ligation. We report a typical case that we found at cesarean section to be associated with a virilized infant who manifested clitoromegaly and labial fusion. We detected an increased level of testosterone in the maternal patient. We concluded that the ovarian luteoma induced the fetal virilization.
Hiromi Ugaki; Takayuki Enomoto; Yoshihiro Tokugawa; Tadashi Kimura
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The journal of obstetrics and gynaecology research     Volume:  35     ISSN:  1447-0756     ISO Abbreviation:  J. Obstet. Gynaecol. Res.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2010-02-12     Completed Date:  2010-05-03     Revised Date:  2012-01-19    
Medline Journal Info:
Nlm Unique ID:  9612761     Medline TA:  J Obstet Gynaecol Res     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  991-3     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Osaka University, Graduate School of Medicine, Osaka, Japan.
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MeSH Terms
Cesarean Section
Infant, Newborn
Luteoma / blood,  complications*
Maternal-Fetal Exchange
Ovarian Neoplasms / blood,  complications*
Pregnancy Complications, Neoplastic / diagnosis
Testosterone / blood
Virilism / blood,  etiology*
Reg. No./Substance:

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