| Luteinizing hormone increases platelet-derived growth factor-D gene expression in human granulosa-luteal cells. | |
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MedLine Citation:
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PMID: 19733850 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We aimed to investigate the effects of LH and FSH on the gene expression of the platelet-derived growth factor (PDGF) gene family in human granulosa-luteal cells. We found that LH significantly increased PDGF-D messenger RNA (mRNA) expression but suppressed PDGF-B and PDGF-C mRNA in human granulosa-luteal cells, and FSH also increases PDGF-D gene expression, but to a lesser extent. |
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Authors:
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Yuh-Ming Hwu; Sheng-Hsiang Li; Robert Kuo-kuang Lee; Ming-Huei Lin; Yu-Hui Tsai; Tien-Shun Yeh |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-09-05 |
Journal Detail:
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Title: Fertility and sterility Volume: 92 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-12-07 Completed Date: 2010-01-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 2065-8 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cells, Cultured Corpus Luteum / cytology* Female Gene Expression / drug effects Granulosa Cells / drug effects, metabolism* Humans Luteinizing Hormone / metabolism*, pharmacology Lymphokines / genetics* Ovarian Follicle / cytology Platelet-Derived Growth Factor / genetics* Proto-Oncogene Proteins c-sis / genetics RNA, Messenger / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Lymphokines; 0/PDGFD protein, human; 0/Platelet-Derived Growth Factor; 0/Proto-Oncogene Proteins c-sis; 0/RNA, Messenger; 0/platelet-derived growth factor C; 9002-67-9/Luteinizing Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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