Document Detail


Lutein absorption in premature infants.
MedLine Citation:
PMID:  20461100     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objective of this study was to measure lutein and zeaxanthin plasma levels after oral lutein administration in preterm infants. Lutein was given orally in a single dose of 0.5 mg/kg to 10 preterm infants at a mean age of 52 h of life. Plasma lutein and zeaxanthin were measured before and 6, 24, 48, and 120 h after lutein administration. All infants had detectable plasma levels of lutein and zeaxanthin before treatment. Lutein concentration increased by 13.5% at 6 h and by 16.7% at 24 h, and returned to the basal level at 120 h after treatment. Zeaxanthin remained unchanged during the study period. Lutein is well absorbed in preterm infants when given orally. The clinical impact of increasing plasma lutein concentrations on macular development and visual function needs further investigation.
Authors:
C Romagnoli; C Tirone; S Persichilli; J Gervasoni; C Zuppi; G Barone; E Zecca
Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2010-05-12
Journal Detail:
Title:  European journal of clinical nutrition     Volume:  64     ISSN:  1476-5640     ISO Abbreviation:  Eur J Clin Nutr     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-07     Completed Date:  2011-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804070     Medline TA:  Eur J Clin Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  760-1     Citation Subset:  IM    
Affiliation:
Division of Neonatology, Department of Paediatrics, Catholic University of the Sacred Heart, Rome, Italy. cromagnoli@rm.unicatt.it
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Humans
Infant, Newborn
Infant, Premature / blood*
Intestinal Absorption
Lutein / administration & dosage,  blood,  pharmacokinetics*
Xanthophylls / blood*
Chemical
Reg. No./Substance:
0/Xanthophylls; 127-40-2/Lutein; 144-68-3/zeaxanthin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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