| Lupus anticoagulant as a risk factor for cerebral infarction and habitual abortions. | |
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MedLine Citation:
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PMID: 2517545 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case involving a 34-year-old female with a progressive hemiparesis is described. She had a history of repeated spontaneous abortions. The CT and magnetic resonance imaging (MRI) showed a multiple cerebral infarction. A 99mTc perfusion lung scintigram demonstrated diffuse bilateral perfusion defects in the lungs. The presence of lupus anticoagulant (LA) was detected from the laboratory data and the thrombosis in the genital organ. The repeated abortions were probably due to thrombosis in the placental vessels caused by LA. High dose steroid therapy was effective in suppressing the LA activity and in preventing progression of the clinical symptoms. |
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Authors:
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K Mizoguchi; S Kakisako; M Tanaka; H Yano; T Shimizu; Y Gondoh; H Shoji; M Kaji |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Kurume medical journal Volume: 36 ISSN: 0023-5679 ISO Abbreviation: Kurume Med J Publication Date: 1989 |
Date Detail:
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Created Date: 1990-06-11 Completed Date: 1990-06-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 2985210R Medline TA: Kurume Med J Country: JAPAN |
Other Details:
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Languages: eng Pagination: 113-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Habitual
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etiology* Adult Blood Coagulation Factors / immunology*, physiology Cerebral Infarction / drug therapy, etiology* Female Hemiplegia / etiology Humans Lupus Coagulation Inhibitor Prednisolone / therapeutic use Pregnancy Risk Factors |
| Chemical | |
Reg. No./Substance:
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0/Blood Coagulation Factors; 0/Lupus Coagulation Inhibitor; 50-24-8/Prednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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