Document Detail

Lupus nephritis mimicking pyelonephritis in pregnancy.
MedLine Citation:
PMID:  20701473     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Systemic lupus erythematosis (SLE) is a multisystemic autoimmune connective tissue disorder that presents with a wide range of clinical manifestations including renal involvement. Routine prenatal care includes assessment of renal function.
CASE: A 29-year-old nullipara presented at 17 weeks with fever, vomiting, and costovertebral angle tenderness 1 week after being treated for a presumed urinary tract infection. On presentation, new-onset hypertension was noted. Inpatient evaluation established a diagnosis of SLE with lupus nephritis. The pregnancy ended with intrauterine fetal demise.
CONCLUSION: SLE is a disease with complex and protean clinical manifestations. It should appear on the differential when more common disease processes are ruled out. Routine prenatal care can detect otherwise silent and undiagnosed renal disease, and with early intervention improve prognosis.
Alexander Friedman; Tanya L Dailey; Douglas Shemin; Brenna L Anderson
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Hypertension in pregnancy     Volume:  29     ISSN:  1525-6065     ISO Abbreviation:  Hypertens Pregnancy     Publication Date:  2010  
Date Detail:
Created Date:  2010-09-27     Completed Date:  2011-01-14     Revised Date:  2014-07-23    
Medline Journal Info:
Nlm Unique ID:  9421297     Medline TA:  Hypertens Pregnancy     Country:  England    
Other Details:
Languages:  eng     Pagination:  478-83     Citation Subset:  IM    
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MeSH Terms
Diagnosis, Differential
Fetal Death
Lupus Nephritis / pathology*
Pregnancy Complications / pathology*
Pyelonephritis / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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