| Lupeol Supplementation Improves Blood Pressure and Lipid Metabolism Parameters in Stroke-Prone Spontaneously Hypertensive Rats. | |
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MedLine Citation:
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PMID: 22232260 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Supplementation with lupeol (0.67 g·kg(-1)) of the AIN-93M-based diet fed for 7 weeks to stroke-prone spontaneously hypertensive rats caused significantly decreased blood pressure as compared with a control group. Urinary 8-hydroxy-2'-deoxyguanosine was significantly lower in the lupeol group. Finally, lupeol suppressed the hepatic mRNA expression levels of the genes involved in triglyceride and cholesterol synthesis. |
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Authors:
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Ardiansyah; Eri Yamaguchi; Hitoshi Shirakawa; Keishi Hata; Kazuyuki Hiwatashi; Kousaku Ohinata; Tomoko Goto; Michio Komai |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-7 |
Journal Detail:
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Title: Bioscience, biotechnology, and biochemistry Volume: - ISSN: 1347-6947 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9205717 Medline TA: Biosci Biotechnol Biochem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Laboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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