Document Detail

Lung recruitment maneuver depresses central hemodynamics in patients following cardiac surgery.
MedLine Citation:
PMID:  16096751     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the impact of the lung recruitment maneuver on circulation following cardiac surgery. DESIGN AND SETTING: Prospective randomized cross-over study at the Departments of Anesthesia and Thoracic Surgery, Copenhagen University Hospital. PATIENTS: Ten adult undergoing coronary artery bypass surgery. INTERVENTIONS: Patients were randomized to two durations of lung recruitment maneuvers (40 cmH2O airway pressure for 10 s and 20 s or vice versa after 5 min) administered immediately after surgery. MEASUREMENTS AND RESULTS: Transesophageal echocardiography (left ventricular short axis view), pulse contour cardiac output, and arterial blood pressure were monitored continuously. Systemic and pulmonary arterial blood gases were sampled before and after each lung recruitment maneuver to calculate the intrapulmonary shunt. Left ventricular end-diastolic areas decreased significantly during both the 10-s and the 20-s lung recruitment maneuvers. Cardiac output was 5.6+/-0.8 l/min at baseline, decreasing by 3.0+/-1.1 l/min and 3.6+/-1.2 l/min during lung recruitment maneuvers of 10 and 20 s, respectively. Shunt decreased from 20+/-5% to 15+/-6% after the first lung recruitment maneuver and from 15+/-6% to 12+/-5% after the second. CONCLUSIONS: Lung recruitment maneuvers markedly reduced cardiac output and left ventricular end-diastolic areas in hemodynamically stable patients following cardiac surgery.
Jonas Nielsen; Morten Østergaard; Jesper Kjaergaard; Jens Tingleff; Preben G Berthelsen; Eigil Nygård; Anders Larsson
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2005-08-12
Journal Detail:
Title:  Intensive care medicine     Volume:  31     ISSN:  0342-4642     ISO Abbreviation:  Intensive Care Med     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-19     Completed Date:  2006-01-05     Revised Date:  2007-10-30    
Medline Journal Info:
Nlm Unique ID:  7704851     Medline TA:  Intensive Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1189-94     Citation Subset:  IM    
Department of Anesthesia and Intensive Care Medicine, Copenhagen University Hospital Gentofte, Niels Andersens Vej 64, 2900 Hellerup, Denmark.
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MeSH Terms
Cardiac Output*
Coronary Artery Bypass*
Echocardiography, Transesophageal
Heart Rate*
Lung Compliance / physiology*
Middle Aged
Postoperative Period
Comment In:
Intensive Care Med. 2006 Mar;32(3):477-8; author reply 479   [PMID:  16496204 ]
Intensive Care Med. 2005 Sep;31(9):1148-9   [PMID:  16096750 ]
Intensive Care Med. 2006 Jan;32(1):177-8   [PMID:  16283161 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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