| Lung nodule detection in low-dose and thin-slice computed tomography. | |
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MedLine Citation:
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PMID: 18342844 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A computer-aided detection (CAD) system for the identification of small pulmonary nodules in low-dose and thin-slice CT scans has been developed. The automated procedure for selecting the nodule candidates is mainly based on a filter enhancing spherical-shaped objects. A neural approach based on the classification of each single voxel of a nodule candidate has been purposely developed and implemented to reduce the amount of false-positive findings per scan. The CAD system has been trained to be sensitive to small internal and sub-pleural pulmonary nodules collected in a database of low-dose and thin-slice CT scans. The system performance has been evaluated on a data set of 39 CT containing 75 internal and 27 sub-pleural nodules. The FROC curve obtained on this data set shows high values of sensitivity to lung nodules (80-85% range) at an acceptable level of false positive findings per patient (10-13 FP/scan). |
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Authors:
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A Retico; P Delogu; M E Fantacci; I Gori; A Preite Martinez |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2008-03-14 |
Journal Detail:
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Title: Computers in biology and medicine Volume: 38 ISSN: 0010-4825 ISO Abbreviation: Comput. Biol. Med. Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-03-31 Completed Date: 2008-09-22 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 1250250 Medline TA: Comput Biol Med Country: United States |
Other Details:
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Languages: eng Pagination: 525-34 Citation Subset: IM |
Affiliation:
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Istituto Nazionale di Fisica Nucleare, Sezione di Pisa, Largo Pontecorvo 3, 56127 Pisa, Italy. retico@df.unipi.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms Artificial Intelligence* Diagnosis, Computer-Assisted* Humans Image Processing, Computer-Assisted* Imaging, Three-Dimensional* Italy Lung / radiography Lung Neoplasms / radiography* Mass Screening Neural Networks (Computer) Pattern Recognition, Automated ROC Curve Radiation Dosage Sensitivity and Specificity Software Solitary Pulmonary Nodule / radiography* Tomography, Spiral Computed* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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