Document Detail

Lung-function tests in neonates and infants with chronic lung disease: tidal breathing and respiratory control.
MedLine Citation:
PMID:  16555264     Owner:  NLM     Status:  MEDLINE    
This paper is the fourth in a series of reviews that will summarize available data and critically discuss the potential role of lung-function testing in infants with acute neonatal respiratory disorders and chronic lung disease of infancy. The current paper addresses information derived from tidal breathing measurements within the framework outlined in the introductory paper of this series, with particular reference to how these measurements inform on control of breathing. Infants with acute and chronic respiratory illness demonstrate differences in tidal breathing and its control that are of clinical consequence and can be measured objectively. The increased incidence of significant apnea in preterm infants and infants with chronic lung disease, together with the reportedly increased risk of sudden unexplained death within the latter group, suggests that control of breathing is affected by both maturation and disease. Clinical observations are supported by formal comparison of tidal breathing parameters and control of breathing indices in the research setting.
David N Baldwin; J Jane Pillow; Janet Stocks; Urs Frey
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Pediatric pulmonology     Volume:  41     ISSN:  8755-6863     ISO Abbreviation:  Pediatr. Pulmonol.     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-04-03     Completed Date:  2006-10-19     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  8510590     Medline TA:  Pediatr Pulmonol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  391-419     Citation Subset:  IM    
Centre for Child Health Research and Telethon Institute for Child Health Research, University of Western Australia, Perth, Western Australia, Australia.
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MeSH Terms
Anoxia / physiopathology
Caffeine / pharmacology
Central Nervous System Stimulants / pharmacology
Chemoreceptor Cells / physiology
Chronic Disease
Feedback, Physiological / physiology
Infant, Newborn / physiology*
Lung Diseases / physiopathology*
Lung Volume Measurements
Maternal Exposure
Posture / physiology
Quality Control
Respiration* / genetics
Respiratory Function Tests*
Sleep / physiology
Tidal Volume / physiology
Reg. No./Substance:
0/Central Nervous System Stimulants; 58-08-2/Caffeine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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