Document Detail

Lung function and cardiopulmonary exercise capacity in patients with corrected tetralogy of Fallot.
MedLine Citation:
PMID:  18847150     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Since surgical repair of tetralogy of Fallot was introduced, follow-up studies have shown that the majority of patients lead active lives and have no subjective exercise limitation. OBJECTIVES: To examine lung function, cardiopulmonary functional capacity and echo-Doppler assessment of pulmonary pressure in adult patients 20 years after repair of TOF. METHODS: Unselected consecutive patients performed full lung function testing, progressive cardiopulmonary exercise, and echo-Doppler assessments of pulmonary pressure. RESULTS: Fifty consecutive patients (33 men, 17 women) aged 29 +/- 11 years who underwent surgical repair of TOF at age 10.1 +/- 10.9 years were enrolled. Patients after TOF showed no restriction (forced expiratory vital capacity 80%, total lung capacity 91%) and had normal oxygen saturation (97%) and 6 minute walking distance (600 meters). Echocardiography showed normal pulmonary pressure and left ventricular ejection function (62%). Cardiopulmonary exercise testing showed mild limitation of exercise capacity with oxygen uptake at maximal effort of 75-78% predicted. CONCLUSIONS: After corrections of TOF the study patients had normal lung function and pulmonary arterial pressure but mild limitation in their exercise capacity.
Gabriel Izbicki; Gershon Fink; Avi Algom; Rafael Hirsch; Leonard Blieden; Eliezer Klainman; Elie Picard; Shmuel Goldberg; Mordechai R Kramer
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Israel Medical Association journal : IMAJ     Volume:  10     ISSN:  1565-1088     ISO Abbreviation:  Isr. Med. Assoc. J.     Publication Date:    2008 Aug-Sep
Date Detail:
Created Date:  2008-10-13     Completed Date:  2008-11-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100930740     Medline TA:  Isr Med Assoc J     Country:  Israel    
Other Details:
Languages:  eng     Pagination:  564-7     Citation Subset:  IM    
Institute of Pulmonology, Shaare Zedek Medical Center and Hebrew University Medical School, Jerusalem, Israel.
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MeSH Terms
Echocardiography, Doppler
Exercise Test
Exercise Tolerance*
Middle Aged
Respiratory Function Tests*
Tetralogy of Fallot / physiopathology,  surgery*,  ultrasonography

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