| Lung function and cardiopulmonary exercise capacity in patients with corrected tetralogy of Fallot. | |
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MedLine Citation:
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PMID: 18847150 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Since surgical repair of tetralogy of Fallot was introduced, follow-up studies have shown that the majority of patients lead active lives and have no subjective exercise limitation. OBJECTIVES: To examine lung function, cardiopulmonary functional capacity and echo-Doppler assessment of pulmonary pressure in adult patients 20 years after repair of TOF. METHODS: Unselected consecutive patients performed full lung function testing, progressive cardiopulmonary exercise, and echo-Doppler assessments of pulmonary pressure. RESULTS: Fifty consecutive patients (33 men, 17 women) aged 29 +/- 11 years who underwent surgical repair of TOF at age 10.1 +/- 10.9 years were enrolled. Patients after TOF showed no restriction (forced expiratory vital capacity 80%, total lung capacity 91%) and had normal oxygen saturation (97%) and 6 minute walking distance (600 meters). Echocardiography showed normal pulmonary pressure and left ventricular ejection function (62%). Cardiopulmonary exercise testing showed mild limitation of exercise capacity with oxygen uptake at maximal effort of 75-78% predicted. CONCLUSIONS: After corrections of TOF the study patients had normal lung function and pulmonary arterial pressure but mild limitation in their exercise capacity. |
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Authors:
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Gabriel Izbicki; Gershon Fink; Avi Algom; Rafael Hirsch; Leonard Blieden; Eliezer Klainman; Elie Picard; Shmuel Goldberg; Mordechai R Kramer |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Israel Medical Association journal : IMAJ Volume: 10 ISSN: 1565-1088 ISO Abbreviation: Isr. Med. Assoc. J. Publication Date: 2008 Aug-Sep |
Date Detail:
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Created Date: 2008-10-13 Completed Date: 2008-11-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100930740 Medline TA: Isr Med Assoc J Country: Israel |
Other Details:
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Languages: eng Pagination: 564-7 Citation Subset: IM |
Affiliation:
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Institute of Pulmonology, Shaare Zedek Medical Center and Hebrew University Medical School, Jerusalem, Israel. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Echocardiography, Doppler Exercise Test Exercise Tolerance* Female Humans Male Middle Aged Respiratory Function Tests* Tetralogy of Fallot / physiopathology, surgery*, ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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