Document Detail

Lung function after deep hypothermic cardiopulmonary bypass in infants.
MedLine Citation:
PMID:  14681094     Owner:  NLM     Status:  MEDLINE    
There is increasing concern about neurologic injury due to deep hypothermia with low flow during repair of complex congenital heart defects in neonates and infants. Twenty infants with ventricular septal defect and pulmonary hypertension were randomly assigned to cardiac repair under deep hypothermia with circulatory arrest or deep hypothermia with low flow. Measurements of static pulmonary compliance, airway resistance, and respiratory index were performed before institution of cardiopulmonary bypass and at 5 minutes and 2 hours after cessation of cardiopulmonary bypass. Both groups had significant pulmonary dysfunction in terms of static pulmonary compliance, airway resistance, and respiratory index. There was greater impairment of pulmonary compliance and respiratory index after deep hypothermia with low flow, and this group required longer intensive care unit stay.
Zhao Kang Su; Yong Sun; Yan Min Yang; Hai Bo Zhang; Zhi Wei Xu
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Asian cardiovascular & thoracic annals     Volume:  11     ISSN:  0218-4923     ISO Abbreviation:  Asian Cardiovasc Thorac Ann     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2003-12-18     Completed Date:  2004-02-18     Revised Date:  2008-09-14    
Medline Journal Info:
Nlm Unique ID:  9503417     Medline TA:  Asian Cardiovasc Thorac Ann     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  328-31     Citation Subset:  IM    
Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, Xinua Hospital, Shanghai Second Medical University, Shanghai 200127, People's Republic of China.
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MeSH Terms
Cardiopulmonary Bypass / adverse effects*
Central Nervous System Diseases / etiology,  prevention & control*
Heart Arrest, Induced / adverse effects*
Heart Septal Defects, Ventricular / surgery
Hypertension, Pulmonary / surgery
Respiratory Function Tests

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