| Lung carcinoma of sheep (jaagsiekte): tissue-bound precipitating antibodies. | |
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MedLine Citation:
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PMID: 283268 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Firmly bound IgG was examined and its activity was tested in spontaneous lung carcinoma of sheep (jaagsiekte). High levels of IgG were extracted by acid-glycine buffer (GB) at pH 2.8 from both the tumor tissue and normal lung, which were exhaustively prewashed by phosphate-buffered saline (PBS) at pH 7.4. The first acid-GB eluates of the normal or tumor tissue acted in the immunodiffusion test as precipitating antibodies against antigens of the first PBS eluate of the tumor tissue. In addition, free intracytoplasmic type A particles were observed in cell-free tumor extract. |
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Authors:
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I Hod; R Milchan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the National Cancer Institute Volume: 62 ISSN: 0027-8874 ISO Abbreviation: J. Natl. Cancer Inst. Publication Date: 1979 Feb |
Date Detail:
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Created Date: 1979-04-25 Completed Date: 1979-04-25 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7503089 Medline TA: J Natl Cancer Inst Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 371-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antibodies / isolation & purification* Antibody Specificity Immunoglobulin G Inclusion Bodies, Viral Lung / immunology Pulmonary Adenomatosis, Ovine / immunology*, pathology Sheep |
| Chemical | |
Reg. No./Substance:
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0/Antibodies; 0/Immunoglobulin G |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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