Document Detail

Lung cancer producing interleukin-6.
MedLine Citation:
PMID:  8785456     Owner:  NLM     Status:  MEDLINE    
A patient with complaints of high fever and left shoulder pain was found to have a large mass in the left upper lobe on chest roentgenogram. Laboratory evaluation revealed marked thrombocytosis, hypoalbuminemia, and increased serum concentrations of CRP, fibrinogen and interleukin-6 (IL-6). A transcutaneous biopsy specimen revealed large cell carcinoma. Tumor production of IL-6 was confirmed by immunohistochemical staining with an anti-human IL-6 monoclonal antibody (MH60).
E Takeuchi; M Ito; M Mori; T Yamaguchi; M Nakagawa; S Yokota; H Nishikawa; J Sakuma-Mochizuki; S Hayashi; T Ogura
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  35     ISSN:  0918-2918     ISO Abbreviation:  Intern. Med.     Publication Date:  1996 Mar 
Date Detail:
Created Date:  1996-09-25     Completed Date:  1996-09-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  212-4     Citation Subset:  IM    
Department of Internal Medicine, Toneyama National Hospital, Osaka.
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MeSH Terms
C-Reactive Protein / metabolism
Carcinoma, Large Cell / pathology,  radiography,  secretion*
Fatal Outcome
Fibrinogen / metabolism
Interleukin-6 / secretion*
Lung Neoplasms / pathology,  radiography,  secretion*
Middle Aged
Reg. No./Substance:
0/Interleukin-6; 9001-32-5/Fibrinogen; 9007-41-4/C-Reactive Protein

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