Document Detail


Lung cancer in the pregnant woman: to treat or not to treat, that is the question.
MedLine Citation:
PMID:  19896236     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lung cancer in pregnancy is a rare situation; however, it is increasingly reported in the past two decades. The association might be more encountered in the coming years due to the rising trends of cigarette smoking among young women and tendency to delay pregnancy to later in life. We performed a literature search without any date or language restriction and identified 44 cases diagnosed and/or treated for lung cancer during the course of pregnancy. Patients had poor post-partum outcome with less than one-forth alive at 1 year following delivery. There was a high incidence of metastases to the products of conception reaching 26%. Eight patients were treated with systemic therapies during the course of gestation with normal fetal outcome and no evidence of fetal or placental metastases. Counseling of these patients is very important. Apart from the clinical conflict they pose, some ethical aspects should be taken in consideration. The poor maternal prognosis should be discussed and the patient's autonomy should be respected to decide whether she wants to keep the pregnancy or not.
Authors:
Hatem A Azim; Fedro A Peccatori; Nicholas Pavlidis
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Publication Detail:
Type:  Journal Article; Review     Date:  2009-11-05
Journal Detail:
Title:  Lung cancer (Amsterdam, Netherlands)     Volume:  67     ISSN:  1872-8332     ISO Abbreviation:  Lung Cancer     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-15     Completed Date:  2010-04-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8800805     Medline TA:  Lung Cancer     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  251-6     Citation Subset:  IM    
Affiliation:
Department of Medical Oncology, National Cancer Institute, Cairo University, Mohandeseen, Cairo, Egypt. hatemazim@cairocure.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Female
Fetus / pathology
Humans
Lung Neoplasms / diagnosis,  pathology,  therapy*
Magnetic Resonance Imaging
Neoplasm Metastasis
Placenta / pathology
Pregnancy
Pregnancy Complications, Neoplastic / diagnosis,  pathology,  therapy*
Prognosis
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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