| Lumped Parameter Model for Heart Failure with Novel Regulating Mechanisms of Peripheral Resistance and Vascular Compliance. | |
| | |
MedLine Citation:
|
PMID: 22395118 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
To research the change in the physiological mechanism between the heart failure (HF) patient and healthy persons, the physiology parameters, which include the myocardial contractility, systemic vascular resistance (SVR), and vascular compliance, were studied. Through clinical data of HF patients, the computing method of the myocardial contractility was proposed; SVR as a function with respect to mean arterial pressure (MAP) was represented; and the vascular compliance was defined as a function with respect to MAP and cardiac output. Based on these parameters, a lumped parameter model of the cardiovascular system was established to reproduce the hemodynamic status of HF patients and verify the validity of the physiological mechanism. The simulation results demonstrate that the proportional error of mean flow, arterial pressure, and systolic blood pressure is 11.9%, 2.3%, and 4.7% compared with the clinical data, respectively. The proportional error of end-diastolic volume, end-systolic volume, and ejection fraction is 13.4%, 3%, and 3.9%, respectively. |
| | |
Authors:
|
Kaiyun Gu; Yu Chang; Bin Gao; Youjun Liu; Zhe Zhang; Feng Wan |
Related Documents
:
|
9465988 - Poland and u.s. collaborative study on cardiovascular epidemiology hypertension in the ... 12044338 - Xanthine oxidase activation in mild gestational hypertension. 10451768 - Management of acute severe hypertension and encephalopathy. 12797128 - The interpretation of uterine artery pulsatility index in normal and hypertensive pregn... 6625218 - Cardiovascular responses to asphyxial challenge in chronically hypokalemic dogs. 475168 - Low-pressure cardiac tamponade. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-3-4 |
Journal Detail:
|
Title: ASAIO journal (American Society for Artificial Internal Organs : 1992) Volume: - ISSN: 1538-943X ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
|
Created Date: 2012-3-7 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9204109 Medline TA: ASAIO J Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
*School of Life Science and BioEngineering, Beijing University of Technology, Beijing, People's Republic of China †Peking University Third Hospital, Beijing, People's Republic of China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Derived and Displayed Power Consumption, Flow, and Pulsatility Over a Range of HeartMate II Left Ven...
Next Document: Thromboresistance Characterization of Extruded Nitric Oxide-Releasing Silicone Catheters.