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Luminex-based virtual crossmatching facilitates combined third-time cardiac and de novo renal transplantation in a sensitized patient with sustained antibody-mediated cardiac allograft rejection.
MedLine Citation:
PMID:  19775252     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Allosensitization represents a major obstacle to successful re-transplantation since circulating antibodies can elicit antibody-mediated rejection episodes with subsequent graft failure. Since sensitization is primarily considered a contraindication to transplantation the duration for patients waiting for a suitable donor organ to become available is considerably prolonged. Herein, we report on the successful application of a Luminex-based virtual crossmatch approach to facilitate combined third-time cardiac and de novo renal transplantation in a sensitized patient with sustained antibody-mediated cardiac allograft rejection.
Authors:
Marcus-André Deutsch; Teresa Kauke; Sebastian Sadoni; Sieglinde Kofler; Daniel Schmauss; Amir K Bigdeli; Max Weiss; Bruno Reichart; Ingo Kaczmarek
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric transplantation     Volume:  14     ISSN:  1399-3046     ISO Abbreviation:  Pediatr Transplant     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9802574     Medline TA:  Pediatr Transplant     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  E96-E100     Citation Subset:  IM    
Copyright Information:
© 2009 John Wiley & Sons A/S.
Affiliation:
Department of Cardiac Surgery, University Hospital Grosshadern, Ludwig-Maximilians-University, Marchioninistrasse, Munich, Germany.
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