Document Detail

Lumbar spine bone measurements in infants: whole-body vs lumbar spine dual X-ray absorptiometry scans.
MedLine Citation:
PMID:  11940725     Owner:  NLM     Status:  MEDLINE    
Availability of software delineation of the lumbar spine region from infant whole-body (IWB) dual energy X-ray absorptiometry scan offers an opportunity to gain additional information at the lumbar spine without a separate scan, although the validity of this technique has never been tested. Lumbar spine measurements derived from IWB scans using software-delineated first to fourth lumbar vertebrae, and from specific infant spine (IS) scans, were determined in 111 infants using two pencil-beam densitometers. Intraoperator repeatability determined by reanalysis of 10 pairs of IWB and IS scans from each densitometer. Lumbar spine area, bone mineral content, and bone mineral density from IWB and IS scans were significantly correlated r = 0.68-0.95, p < 0.001 for all comparisons) but show poor agreement (Bland-Altman method) with one SD of the differences equal to 26-55% of the mean. Intraoperator reanalysis shows good agreement with one SD of the differences from IWB scans at <7% of the mean, and <2.9% from IS scans. Findings were the same for both densitometers. We conclude that lumbar spine bone measurements from IWB or IS scans are highly reproducible and significantly correlated but data from IWB scans cannot substitute for data from IS scans.
Mohammad Zia-Ullah; Winston W K Koo; Mouhanad Hammami
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry     Volume:  5     ISSN:  1094-6950     ISO Abbreviation:  J Clin Densitom     Publication Date:  2002  
Date Detail:
Created Date:  2002-04-09     Completed Date:  2002-08-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9808212     Medline TA:  J Clin Densitom     Country:  United States    
Other Details:
Languages:  eng     Pagination:  17-25     Citation Subset:  IM    
Department of Pediatrics, Wayne State University, Detroit, MI 48201, USA.
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MeSH Terms
Absorptiometry, Photon / methods
Cohort Studies
Lumbar Vertebrae / physiology*
Reproducibility of Results
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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