Document Detail

Lumbar puncture in neonates under and over 72 hours of age.
MedLine Citation:
PMID:  16899181     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To identify the criteria for performing a spinal tap in neonates with suspected sepsis and compare the findings in infants under and over the age of 72 hours. STUDY DESIGN: Analytical. PLACE AND DURATION: Neonatal Ward of Taleghani Medical Centre, Shaheed Beheshti University of Medical Sciences, Evin,Tehran. Study period was of one year, from March 2003 to February 2004. PATIENTS AND METHODS: All newborns subjected to a lumbar puncture during the first 24 hours of admission were enrolled in the study. Results of cerebrospinal fluid analysis were scrutinized. RESULTS: There were 380 neonates in the study. Majority i.e. 248 infants were aged<72 hours. Meningitis was diagnosed in 22 cases, (5.8%). There was no significant difference in the incidence of meningitis between neonates under and over 72 hours of age, (6.9% vs. 3.8%, p-value>0.5). Comparison of risk factors, clinical manifestations, and routine laboratory investigations revealed no significant difference in babies with or without meningitis. CONCLUSION: The findings of this series do not support a selective approach for performing a lumbar puncture in a possibly septic newborn. A lumbar puncture is recommended in all neonates with suspected sepsis regardless of age, risk factors, or specific neurological manifestations.
Farideh Shiva; Nariman Mosaffa; Ronak Khabbaz; Mojgan Padyab
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of the College of Physicians and Surgeons--Pakistan : JCPSP     Volume:  16     ISSN:  1022-386X     ISO Abbreviation:  J Coll Physicians Surg Pak     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-08-10     Completed Date:  2006-11-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606447     Medline TA:  J Coll Physicians Surg Pak     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  525-8     Citation Subset:  IM    
Department of Pediatrics, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.
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MeSH Terms
Age Factors
Follow-Up Studies
Gram-Negative Bacterial Infections / cerebrospinal fluid,  diagnosis,  epidemiology
Gram-Positive Bacterial Infections / cerebrospinal fluid,  diagnosis,  epidemiology
Infant, Newborn
Meningitis, Bacterial / cerebrospinal fluid,  diagnosis,  epidemiology
Risk Factors
Sepsis / cerebrospinal fluid,  diagnosis,  epidemiology
Spinal Puncture*

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