Document Detail

Ludwig's angina: report of two cases and review of the literature from 1945 to January 1979.
MedLine Citation:
PMID:  6932499     Owner:  NLM     Status:  MEDLINE    
Two cases of Ludwig's angina treated successfully led us to review the main English language literature from 1945 to January 1979. The most common cause of Ludwig's angina is dental, and the organism cultured most often is streptococcus. However, other avenues of infection and numerous pathogens have been implicated in this disease. Penicillin remains the preferred primary antibiotic, with combinations of this drug and other antibiotics being used by various authors. In both the pre-antibiotic and antibiotic era, the airway remains the prime concern of the surgeon in the management of this potentially life-threatening disease. Of the 75 cases reviewed, there were seven deaths, but four of these patients had pre-existing fatal systemic problems and Ludwig's angina was not the cause of death. The other three deaths were due to Ludwig's angina, yielding a 4% mortality rate. Thus, aggressive management of Ludwig's angina, with respect to airway, antibiotics, and early surgical intervention, has resulted in a significant drop in the mortality rate of this disease which once led "almost uniformly to a fatal ending."
R T Hought; B E Fitzgerald; J E Latta; R D Zallen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of oral surgery (American Dental Association : 1965)     Volume:  38     ISSN:  0022-3255     ISO Abbreviation:  J Oral Surg     Publication Date:  1980 Nov 
Date Detail:
Created Date:  1980-12-18     Completed Date:  1980-12-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8302454     Medline TA:  J Oral Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  849-55     Citation Subset:  AIM; D; IM    
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MeSH Terms
Ludwig's Angina / etiology,  pathology*
Mandibular Fractures / complications
Tooth Extraction / adverse effects

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