Document Detail

Lucilia cuprina induced hyperammonaemia and alkalosis associated with pathology in sheep.
MedLine Citation:
PMID:  3392704     Owner:  NLM     Status:  MEDLINE    
Gross and microscopical examinations were done in 12 sheep infested with Lucilia cuprina larvae. All the sheep became hyperammonaemic and alkalotic. Six sheep died and 6 survived, one being moribund before euthanasia. Necropsy revealed severe acute dermatitis and congestion of the liver, heart, kidney, spleen and lungs. Ecchymotic haemorrhages were present in the heart, kidneys and adrenal glands of severely infested sheep. Microscopical examination showed mild to severe vacuolation of the central nervous system in all sheep. In severely infested sheep, skin, lung, heart, kidney, and liver tissues were infiltrated by mononuclear cells, neutrophiles or lymphocytes. Fibrin thrombi were present in vessels. Elevated concentrations of lipid soluble ammonia in blood were positively correlated with tissue abnormality and early death.
V H Guerrini; M A Bell; G M Murphy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the South African Veterinary Association     Volume:  59     ISSN:  1019-9128     ISO Abbreviation:  J S Afr Vet Assoc     Publication Date:  1988 Jun 
Date Detail:
Created Date:  1988-08-12     Completed Date:  1988-08-12     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7503122     Medline TA:  J S Afr Vet Assoc     Country:  SOUTH AFRICA    
Other Details:
Languages:  eng     Pagination:  73-6     Citation Subset:  IM    
Vetsearch Australia Pty. Ltd., Daisy Hill, Queensland.
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MeSH Terms
Alkalosis / etiology,  veterinary*
Ammonia / blood*
Sheep / parasitology
Sheep Diseases / blood,  parasitology*
Time Factors
Reg. No./Substance:

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