Document Detail


Lowering of pancreatic amylase activity induced by cold exposure, fasting and adrenalectomy in rats.
MedLine Citation:
PMID:  1709074     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. Alteration of amylase activity in the pancreas was studied in rats under different stressful situations. 2. Cold-exposed rats had reduced amylase activity, hypertrophy of adrenal glands, and lowered plasma insulin and glucose. 3. In fasted rats, amylase activity decreased and plasma insulin and glucose lowered. 4. Immobilized animals failed to produce the reduced amylase activity, despite existence of higher plasma corticosterone. 5. Adrenalectomy caused reduction of amylase activity accompanied by decreases in plasma insulin and glucose. 6. Glucocorticoid hormone is not correlated with suppression of amylase synthesis. The lowered amylase activity might involve changes in glycolytic flux and/or suppression of amylase synthesis by insulin deficiency.
Authors:
E Harada
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Comparative biochemistry and physiology. A, Comparative physiology     Volume:  98     ISSN:  0300-9629     ISO Abbreviation:  Comp Biochem Physiol A Comp Physiol     Publication Date:  1991  
Date Detail:
Created Date:  1991-06-07     Completed Date:  1991-06-07     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  1276312     Medline TA:  Comp Biochem Physiol A Comp Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  333-8     Citation Subset:  IM    
Affiliation:
Department of Physiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adrenal Glands / growth & development,  pathology,  physiology
Adrenalectomy
Amylases / metabolism*
Animals
Blood Glucose / metabolism
Cold Temperature / adverse effects
Fasting / metabolism
Hypertrophy / enzymology
Insulin / blood
Male
Organ Size / physiology
Pancreas / enzymology*,  growth & development
Rats
Rats, Inbred Strains
Restraint, Physical
Stress, Physiological / enzymology*
Chemical
Reg. No./Substance:
0/Blood Glucose; 11061-68-0/Insulin; EC 3.2.1.-/Amylases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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