Document Detail

Lowered risk of nasopharyngeal carcinoma and intake of plant vitamin, fresh fish, green tea and coffee: a case-control study in Taiwan.
MedLine Citation:
PMID:  22848600     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: A case-control study was conducted to evaluate the role of adult diet on nasopharyngeal carcinoma (NPC) in Taiwan.
METHODS: A total of 375 incident NPC cases and 327 controls matched to the cases on sex, age, and residence were recruited between July 1991 and December 1994. A structured questionnaire inquiring complete dietary history, socio-demographic characteristics, and other potential confounding factors was used in the personal interview. Unconditional logistic regression analysis was used to estimate multivariate-adjusted odds ratio (OR(adj)) with 95% confidence interval (CI) after accounting for known risk factors.
RESULTS: Fresh fish (OR(adj), 0.56; 95% CI, 0.38-0.83 for the highest vs. lowest tertile of intake), green tea (OR(adj), 0.61; 95% CI, 0.40-0.91 for drinking ≥1 times/week vs. never) and coffee (OR(adj), 0.56; 95% CI, 0.37-0.85 for drinking ≥0.5 times/week vs. never) were inversely associated with the NPC risk. No association with NPC risk was observed for the intake of meats, salted fish, fresh vegetables, fruits and milk. Intake of vitamin A from plant sources was associated with a decreased NPC risk (OR(adj), 0.62; 95% CI, 0.41-0.94 for the highest vs. lowest tertile).
CONCLUSION: The study findings suggest that certain adult dietary patterns might protect against the development of NPC.
Wan-Lun Hsu; Wen-Harn Pan; Yin-Chu Chien; Kelly J Yu; Yu-Juen Cheng; Jen-Yang Chen; Mei-Ying Liu; Mow-Ming Hsu; Pei-Jen Lou; I-How Chen; Czau-Siung Yang; Allan Hildesheim; Chien-Jen Chen
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Intramural     Date:  2012-07-27
Journal Detail:
Title:  PloS one     Volume:  7     ISSN:  1932-6203     ISO Abbreviation:  PLoS ONE     Publication Date:  2012  
Date Detail:
Created Date:  2012-07-31     Completed Date:  2013-04-09     Revised Date:  2013-07-12    
Medline Journal Info:
Nlm Unique ID:  101285081     Medline TA:  PLoS One     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e41779     Citation Subset:  IM    
Genomics Research Center, Academia Sinica, Taipei, Taiwan.
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MeSH Terms
Case-Control Studies
Middle Aged
Nasopharyngeal Neoplasms / epidemiology*,  prevention & control
Plants / chemistry*
Risk Factors
Taiwan / epidemiology
Reg. No./Substance:
0/Coffee; 0/Tea; 0/Vitamins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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