Document Detail


Lower pole I: a prospective randomized trial of extracorporeal shock wave lithotripsy and percutaneous nephrostolithotomy for lower pole nephrolithiasis-initial results.
MedLine Citation:
PMID:  11696709     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The efficacy of shock wave lithotripsy and percutaneous stone removal for the treatment of symptomatic lower pole renal calculi was determined. MATERIALS AND METHODS: A prospective randomized, multicenter clinical trial was performed comparing shock wave lithotripsy and percutaneous stone removal for symptomatic lower pole only renal calculi 30 mm. or less. RESULTS: Of 128 patients enrolled in the study 60 with a mean stone size of 14.43 mm. were randomized to percutaneous stone removal (58 treated, 2 awaiting treatment) and 68 with a mean stone size of 14.03 mm. were randomized to shock wave lithotripsy (64 treated, 4 awaiting treatment). Followup at 3 months was available for 88% of treated patients. The 3-month postoperative stone-free rates overall were 95% for percutaneous removal versus 37% lithotripsy (p <0.001). Shock wave lithotripsy results varied inversely with stone burden while percutaneous stone-free rates were independent of stone burden. Stone clearance from the lower pole following shock wave lithotripsy was particularly problematic for calculi greater than 10 mm. in diameter with only 7 of 33 (21%) patients becoming stone-free. Re-treatment was necessary in 10 (16%) lithotripsy and 5 (9%) percutaneous cases. There were 9 treatment failures in the lithotripsy group and none in the percutaneous group. Ancillary treatment was necessary in 13% of lithotripsy and 2% percutaneous cases. Morbidity was low overall and did not differ significantly between the groups (percutaneous stone removal 22%, shock wave lithotripsy 11%, p =0.087). In the shock wave lithotripsy group there was no difference in lower pole anatomical measurements between kidneys in which complete stone clearance did or did not occur. CONCLUSIONS: Stone clearance from the lower pole following shock wave lithotripsy is poor, especially for stones greater than 10 mm. in diameter. Calculi greater than 10 mm. in diameter are better managed initially with percutaneous removal due to its high degree of efficacy and acceptably low morbidity.
Authors:
D M Albala; D G Assimos; R V Clayman; J D Denstedt; M Grasso; J Gutierrez-Aceves; R I Kahn; R J Leveillee; J E Lingeman; J N Macaluso; L C Munch; S Y Nakada; R C Newman; M S Pearle; G M Preminger; J Teichman; J R Woods
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Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of urology     Volume:  166     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2001-11-06     Completed Date:  2001-12-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2072-80     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Humans
Kidney Calculi / therapy*
Lithotripsy*
Nephrostomy, Percutaneous*
Prospective Studies
Comments/Corrections
Erratum In:
J Urol 2002 Apr;167(4):1805

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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