| Lower oesophageal sphincter pressure and timed barium oesophagogram: two objective parameters in the non-invasive assessment of primary achalasia. | |
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MedLine Citation:
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PMID: 16091064 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The non-invasive assessment of primary achalasia is not precise. AIM: To compare investigations before and 1 month after balloon dilation in achalasia. METHODS: Fifty-two patients with primary achalasia were enrolled. Subjective and objective variables of oesophageal functions were analysed before and 1 month after balloon dilation. RESULTS: The mean predilation symptom score, lower oesophageal sphincter pressure, height and volume of barium at 5 min were 7.7 +/- 2.6, 62.0 +/- 25.1 mmHg, 9.2 +/- 6.1 cm and 53.2 +/- 49.8 mL respectively; the mean postdilation values were 3.0 +/- 3.0, 34.1 +/- 12.5 mmHg, 7.9 +/- 5.1 cm and 28.0 +/- 30.1 mL respectively. The before dilation volume of barium at 5 min correlates significantly with lower oesophageal sphincter pressure (P < 0.01). The mean symptom scores, lower oesophageal sphincter pressure and volume of barium at 5 min dropped significantly after intervention (P < 0.01), but the reduction in barium height at 5 min was not significant. The percentage changes in volume at 5 min significantly predicted the percentage changes in lower oesophageal sphincter pressure (P < 0.01). CONCLUSIONS: The volume of barium retention at 5 min can predict the lower oesophageal sphincter pressure before and after balloon dilation in primary achalasia. This could be used as a non-invasive objective tool for initial and post-dilation assessment. |
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Authors:
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G Montazeri; N Nouri; A Estakhri; S Shirani; M H Derakhshan; M Yaghoobi; J Mikaeli; R Malekzadeh |
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Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: Alimentary pharmacology & therapeutics Volume: 22 ISSN: 0269-2813 ISO Abbreviation: Aliment. Pharmacol. Ther. Publication Date: 2005 Aug |
Date Detail:
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Created Date: 2005-08-10 Completed Date: 2005-11-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8707234 Medline TA: Aliment Pharmacol Ther Country: England |
Other Details:
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Languages: eng Pagination: 261-5 Citation Subset: IM |
Affiliation:
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Gastroenterology and Hepatology, Digestive Disease Research Center, Tehran University of Medical Science, Shariati Hospital, Tehran, Iran. montazer@ams.ac.ir |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Balloon Dilatation Barium Sulfate / diagnostic use Contrast Media Esophageal Achalasia / diagnosis*, radiography, therapy* Esophageal Sphincter, Lower / physiopathology* Female Humans Male Manometry Middle Aged Observer Variation Pressure Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 7727-43-7/Barium Sulfate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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