Document Detail

Lower limb movement variability in patients with peripheral arterial disease.
MedLine Citation:
PMID:  18495306     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Peripheral arterial disease is a chronic obstructive disease of the arteries of the lower limb caused by atherosclerosis. The resultant decrease in blood flow can result in symptoms of pain in the lower limb on exercise known as intermittent claudication. Exercise induced pain is experienced in the calves, thigh or buttocks restricting activities of daily living and thus reducing quality of life. METHODS: This study investigated lower limb movement variability in individuals with peripheral arterial disease-intermittent claudication (n=28) compared to individuals without peripheral arterial disease-intermittent claudication (control, n=25). A further aim was to examine the efficacy of various techniques used to describe single joint movement variability. All participants underwent two-dimensional angular kinematics analysis of the lower limb during normal walking. Single joint movement variability was measured using linear (spanning set and coefficient of variation) techniques. Between group differences were examined by one-way ANOVA. FINDINGS: The peripheral arterial disease-intermittent claudication participants displayed significantly higher levels of lower limb movement variability in all joints when assessed using the coefficient of variation technique. There were no significant between group differences using the spanning set technique. INTERPRETATION: Individuals with peripheral arterial disease-intermittent claudication have higher levels of lower limb movement variability and reduced walking speed compared to healthy age and mass matched controls. This variability may be an adaptation to the gradual onset of ischaemic pain in this population.
Robert G Crowther; Warwick L Spinks; Anthony S Leicht; Frank Quigley; Jonathan Golledge
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2008-05-20
Journal Detail:
Title:  Clinical biomechanics (Bristol, Avon)     Volume:  23     ISSN:  0268-0033     ISO Abbreviation:  Clin Biomech (Bristol, Avon)     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-08-25     Completed Date:  2008-11-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8611877     Medline TA:  Clin Biomech (Bristol, Avon)     Country:  England    
Other Details:
Languages:  eng     Pagination:  1080-5     Citation Subset:  IM    
Institute of Sport and Exercise Science, James Cook University, Townsville, Queensland 4811, Australia.
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MeSH Terms
Intermittent Claudication / etiology,  physiopathology
Leg / blood supply,  physiology*,  physiopathology*
Movement / physiology*
Peripheral Vascular Diseases / complications,  physiopathology*
Walking / physiology

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