Document Detail

Lower extremity motor evoked potentials in multiple sclerosis.
MedLine Citation:
PMID:  1953419     Owner:  NLM     Status:  MEDLINE    
Transcranial magnetic stimulation was performed on 25 patients with definite multiple sclerosis. Motor evoked potentials were recorded from the anterior tibial muscle. Central motor conduction time was calculated using the equation (F + M-1)/2 by stimulation of the common peroneal nerve. Motor evoked potentials were capable of detecting subclinical pyramidal tract lesions in multiple sclerosis. In patients with multiple sclerosis, the incidence of abnormality of motor and somatosensory evoked potentials was similar. Central motor conduction time was correlated with overall and pyramidal tract subscores on the Kurtzke Disability Status Scale and the Scripps Neurological Rating Scale. Central motor conduction time abnormalities correlated best with the presence of a Babinski's sign but also correlated significantly with weakness and hyperreflexia.
S M Jones; L J Streletz; V E Raab; R L Knobler; F D Lublin
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of neurology     Volume:  48     ISSN:  0003-9942     ISO Abbreviation:  Arch. Neurol.     Publication Date:  1991 Sep 
Date Detail:
Created Date:  1991-11-22     Completed Date:  1991-11-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372436     Medline TA:  Arch Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  944-8     Citation Subset:  AIM; IM    
Department of Neurology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pa.
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MeSH Terms
Evoked Potentials*
Leg / physiopathology*
Middle Aged
Motor Activity*
Multiple Sclerosis / physiopathology*
Neural Conduction

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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