| Lower extremities magnetic resonance angiography with blood pressure cuff compression: quantitative dynamic analysis. | |
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MedLine Citation:
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PMID: 19472421 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To quantitatively evaluate changes induced by the application of a femoral blood-pressure cuff (BPC) on run-off magnetic resonance angiography (MRA), which is a method generally previously proposed to reduce venous contamination in the leg. MATERIALS AND METHODS: This study was Health Insurance Portability and Accountability Act (HIPAA)- and Institutional Review Board (IRB)-compliant. We used time-resolved gradient-echo gadolinium (Gd)-enhanced MRA to measure BPC effects on arterial, venous, and soft-tissue enhancement. Seven healthy volunteers (six men) were studied with the BPC applied at the mid-femoral level unilaterally using a 1.5 T MR system after intravenous injection of Gd-BOPTA. Different statistical tools were used such as the Wilcoxon signed rank test and a cubic smoothing spline fit. RESULTS: We found that BPC application induces delayed venous filling (as previously described), but also induces significant decreases in arterial inflow, arterial enhancement, vascular-soft tissue contrast, and delayed peak enhancement (which have not been previously measured). CONCLUSION: The potential benefits from using a BPC for run-off MRA must be balanced against the potential pitfalls, elucidated by our findings. |
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Authors:
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Marcel Koenigkam-Santos; Puneet Sharma; Bobby Kalb; John Carew; John N Oshinski; Diego Martin |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 29 ISSN: 1053-1807 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-06-01 Completed Date: 2009-07-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 1450-6 Citation Subset: IM |
Affiliation:
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Department of Radiology, Emory University School of Medicine, Atlanta, Georgia, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Flow Velocity Contrast Media Female Humans Leg / blood supply* Magnetic Resonance Angiography / methods* Male Meglumine / analogs & derivatives Middle Aged Organometallic Compounds Pressure Statistics, Nonparametric |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Organometallic Compounds; 113662-23-0/gadobenic acid; 6284-40-8/Meglumine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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