| Lower esophageal sphincter pressure in Chagas' disease. | |
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MedLine Citation:
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PMID: 2108007 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It is known that lower esophageal sphincter (LES) pressure in patients with idiopathic achalasia is higher than in normal subjects, but in patients with Chagas' disease, who have esophageal disease with similar clinical, manometric, and radiologic results, studies of LES pressure show contradictory findings. We measured the LES pressure in 118 patients with chronic Chagas' disease, 14 patients with idiopathic achalasia, and 50 control subjects using a perfused catheter and the stationary pull-through (SPT) technique. The patients with Chagas' disease had normal esophageal radiologic examination (group A, N = 50), delay in esophageal clearance without dilatation (group B, N = 41), or delay in esophageal clearance with dilatation (group C, N = 27). The LES pressure of Chagas' disease patients of group A (18.6 +/- 9.1 mm Hg, mean +/- SD), group B (17.8 +/- 9.7 mm Hg), and group C (21.6 +/- 10.1 mm Hg) was lower (P less than 0.001) than the LES pressure of the controls (24.9 +/- 10.2 mm Hg). In patients with idiopathic achalasia, the LES pressure (40.7 +/- 17.8 mm Hg) was higher than in control subjects (P less than 0.01) and Chagas' disease patients (P less than 0.001). We conclude that the LES pressure of patients with Chagas' disease tended to be lower than that of control subjects and achalasia patients. |
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Authors:
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R O Dantas; R A Godoy; R B Oliveira; U G Meneghelli; L E Troncon |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Digestive diseases and sciences Volume: 35 ISSN: 0163-2116 ISO Abbreviation: Dig. Dis. Sci. Publication Date: 1990 Apr |
Date Detail:
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Created Date: 1990-05-03 Completed Date: 1990-05-03 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7902782 Medline TA: Dig Dis Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 508-12 Citation Subset: AIM; IM |
Affiliation:
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Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Brazil. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Chagas Disease / physiopathology* Child Esophageal Achalasia / physiopathology Esophagogastric Junction / physiopathology* Female Humans Male Manometry Middle Aged Pressure |
| Comments/Corrections | |
Comment In:
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Dig Dis Sci. 1993 Jul;38(7):1358
[PMID:
8325198
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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