| Lower esophageal sphincter pressure, acid secretion, and blood gastrin after coffee consumption. | |
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MedLine Citation:
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PMID: 1551346 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study tested the hypothesis that differences in the processing of raw coffee beans can account for some of the variability in gastric effects of coffee drinking. Coffees were selected to represent several ways that green coffee beans are treated, ie, processing variables. These included instant and ground coffee processing, decaffeination method (ethyl acetate or methylene chloride extraction), instant coffee processing temperature (112 degrees F or 300 degrees F), and steam treatment. Lower esophageal sphincter pressure, acid secretion, and blood gastrin was measured in eight human subjects after they consumed each of the different coffees. Consumption of coffee was followed by a sustained decrease in lower esophageal sphincter pressure (P less than 0.05) except for three of the four coffees treated with ethyl acetate regardless of whether or not they contained caffeine. Caffeinated ground coffee stimulated more acid secretion that did decaf ground coffees (P less than 0.05), but not more than a steam-treated caffeinated coffee. Instant coffees did not differ in acid-stimulating ability. Ground caffeinated coffee resulted in higher blood gastrin levels than other ground coffees (P less than 0.05). Freeze-dried instant coffee also tended toward higher gastrin stimulation. It is concluded that some of the observed variability in gastric response to coffee consumption can be traced to differences in how green coffee beans are processed. |
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Authors:
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G Van Deventer; E Kamemoto; J T Kuznicki; D C Heckert; M C Schulte |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Digestive diseases and sciences Volume: 37 ISSN: 0163-2116 ISO Abbreviation: Dig. Dis. Sci. Publication Date: 1992 Apr |
Date Detail:
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Created Date: 1992-04-27 Completed Date: 1992-04-27 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7902782 Medline TA: Dig Dis Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 558-69 Citation Subset: AIM; IM |
Affiliation:
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Center for Ulcer Research and Education, Los Angeles, California. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Analysis of Variance Caffeine / blood Coffee / adverse effects* Esophagogastric Junction / physiology* Gastric Acid / secretion* Gastrins / blood* Half-Life Humans Male Pressure Reference Values |
| Chemical | |
Reg. No./Substance:
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0/Coffee; 0/Gastrins; 58-08-2/Caffeine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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