Document Detail


Lower bone mineral density in geriatric patients with monoclonal gammopathy of undetermined significance.
MedLine Citation:
PMID:  17874101     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to investigate the prevalence of monoclonal gammopathy of undetermined significance (MGUS) in a geriatric population in Turkey and compare bone mineral densities and related laboratory parameters of MGUS patients with those who do not have MGUS. Among 1,012 patients enrolled, monoclonal band was detected in serum samples of 22 patients (2.17%), most of which were IgG type. Further tests revealed multiple myeloma and lung carcinoma in two patients. The remaining 20 patients were diagnosed with MGUS (1.97%). The clinical and laboratory parameters of patients with and without MGUS were mostly comparable; however, bone mineral density measurements of patients with MGUS were significantly lower than those without MGUS (p = 0.007). We suggest evaluation of geriatric patients with MGUS for the presence of osteopenia/osteoporosis considering the high frequency observed in this study.
Authors:
Omer Dizdar; Mustafa Erman; Mustafa Cankurtaran; Meltem Halil; Zekeriya Ulger; Burcu Balam Yavuz; Servet Ariogul; Asli Pinar; Hakan Harputluoglu; Ayse Kars; Ismail Celik
Publication Detail:
Type:  Journal Article     Date:  2007-09-14
Journal Detail:
Title:  Annals of hematology     Volume:  87     ISSN:  1432-0584     ISO Abbreviation:  Ann. Hematol.     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-11-21     Completed Date:  2008-04-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9107334     Medline TA:  Ann Hematol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  57-60     Citation Subset:  IM    
Affiliation:
Institute of Oncology, Department of Medical Oncology, Hacettepe University, Sihhiye, Ankara, Turkey. omerdiz@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Female
Humans
Male
Osteoporosis / blood*,  complications*
Paraproteinemias / blood*,  complications*

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