| Lower extremity manifestations and treatment of heparin-induced thrombocytopenia syndromes: a cohort study. | |
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MedLine Citation:
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PMID: 21055974 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Heparin-induced thrombocytopenia (HIT) and heparin-induced thrombocytopenia with thrombosis (HITT) syndromes are the result of an adverse reaction to heparin that results in a spectrum of laboratory and end-organ manifestations secondary to thrombosis of both arterial and venous small and large vessels. HITT most often manifests in the extremities as acral ischemia and necrosis, with a spectrum of severity. The lower extremity surgical patient is at risk for deep venous thrombosis, and when exposed to heparin products, is also at risk for the development of a heparin-induced thrombocytopenic syndrome. This article reports on a cohort of patients from a tertiary referral lower extremity reconstruction practice with the HIT/HITT syndromes, with an analysis of the frequency, medical characteristics, clinical settings, lower extremity manifestations, management, and outcomes of patients with HIT/HITT.). |
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Authors:
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Christopher Bibbo; Philip Shawn Hatfield |
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Publication Detail:
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Type: Journal Article Date: 2010-11-04 |
Journal Detail:
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Title: The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons Volume: 50 ISSN: 1542-2224 ISO Abbreviation: J Foot Ankle Surg Publication Date: 2011 Jan-Feb |
Date Detail:
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Created Date: 2010-12-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9308427 Medline TA: J Foot Ankle Surg Country: United States |
Other Details:
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Languages: eng Pagination: 16-24 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Chief, Foot & Ankle Section, Department of Orthopaedics, Marshfield Clinic, Marshfield, WI. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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