Document Detail


Lower blood pressure goals in high-risk cardiovascular patients: are they defensible?
MedLine Citation:
PMID:  20621249     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This review highlights the paucity of data that support actively decreasing blood pressures (BP) to a level of less than 130/80 mm Hg. Although the data support a lower cardiovascular (CV) event rate with this lower level of pressure in high-risk CV people, early aggressive intervention to prevent levels from going above this mark prevent development of worsening atherosclerosis. Although no trial will ever prove this concept of prevention, common sense and multiple animal experiments support it. Most patients should have their systolic BP reduced to levels well below 140 mm Hg approaching 130 mm Hg, not 140 mm Hg.
Authors:
Keith A Hopkins; George L Bakris
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cardiology clinics     Volume:  28     ISSN:  1558-2264     ISO Abbreviation:  Cardiol Clin     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-12     Completed Date:  2010-11-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8300331     Medline TA:  Cardiol Clin     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  447-52     Citation Subset:  IM    
Copyright Information:
2010 Elsevier Inc. All rights reserved.
Affiliation:
The University of Chicago Pritzker School of Medicine, IL 60637, USA.
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MeSH Terms
Descriptor/Qualifier:
Cardiovascular Diseases / complications,  epidemiology,  therapy*
Diabetes Mellitus, Type 2 / complications,  epidemiology,  therapy*
Female
Humans
Hypertension / complications,  drug therapy*
Male
Middle Aged
Obesity / ethnology,  etiology,  therapy
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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