Document Detail

Low versus high pressure for in vitro determination of hydraulic conductance of human dentine.
MedLine Citation:
PMID:  9222448     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to evaluate the effect of applied pressure and measurement time on the in vitro measurement of hydraulic conductance of human dentine. Dentine slices were prepared from 50 third molars. Water was forced through the slices under a constant hydrostatic pressure. Five pressures were tested: 1.3 kPa (n = 10), 13.3 kPa (n = 10), 26.6 kPa (n = 10), 40 kPa (n = 10) and 53.3 kPa (n = 10). The volume that went through the slices was recorded every 10 min for 3 h. The volume, the fluid flow rate and the hydraulic conductance under the five pressures were compared. The volume increased with time and pressure. The fluid flow and hydraulic conductance decreased with time under 13.3, 26.6 and 40 kPa, but remained constant under 1.3 and 53.3 kPa. Used of a low pressure (1.3 kPa) may permit water to pass through dentinal tubules without disturbing intratubular contents. Medium pressures (13.3, 26.6, 40 kPa) seemed to disturb tubule contents progressively, resulting in decreased fluid flow and therefore a decreased hydraulic conductance with time. Under these pressures, the calculated values of hydraulic conductance may be unreliable because they are time-dependent. High pressure (53.3 kPa) seemed to pack the tubule contents against intratubular resistances immediately, resulting in low fluid flows and low hydraulic conductances.
J Camps; S Giustiniani; J Dejou; J C Franquin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of oral biology     Volume:  42     ISSN:  0003-9969     ISO Abbreviation:  Arch. Oral Biol.     Publication Date:  1997 Apr 
Date Detail:
Created Date:  1997-08-12     Completed Date:  1997-08-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0116711     Medline TA:  Arch Oral Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  293-8     Citation Subset:  D; IM    
IMEB EA 1787, Faculté d'Odontologie, Marseille, France.
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MeSH Terms
Analysis of Variance
Dentin Permeability*
Dentinal Fluid / physiology*
Fluid Shifts
Hydrostatic Pressure
Reference Values
Statistics, Nonparametric

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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