Document Detail


Low- and ultra-low-molecular-weight heparins.
MedLine Citation:
PMID:  15171959     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Heparins and low-molecular-weight heparins (LMWHs) have been the mainstay for the prevention and management of venous and arterial thromboembolic disease. In particular, the LMWHs have become well established in the past 15 years for the prevention of thrombosis in medium- and high-risk surgical and medical patients and in the initial management of venous thromboembolism (VTE). They have also been widely evaluated and adopted in clinical practice in the management of patients with acute coronary syndromes. More recently, a variety of heparin-like drugs have been evaluated as potential antithrombotic agents, and the synthetic pentasaccharide (fondaparinux) has been developed and evaluated for the prevention and treatment of VTE.
Authors:
Ajay K Kakkar
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Best practice & research. Clinical haematology     Volume:  17     ISSN:  1521-6926     ISO Abbreviation:  Best Pract Res Clin Haematol     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-06-02     Completed Date:  2005-02-02     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  101120659     Medline TA:  Best Pract Res Clin Haematol     Country:  England    
Other Details:
Languages:  eng     Pagination:  77-87     Citation Subset:  IM    
Affiliation:
Department of Surgical Oncology and Technology, Faculty of Medicine, Imperial College, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK. akkakkaar@tri-london.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Heparin / therapeutic use*
Heparin, Low-Molecular-Weight / therapeutic use
Humans
Neoplasms / drug therapy
Thrombosis / drug therapy,  prevention & control
Treatment Outcome
Chemical
Reg. No./Substance:
0/Heparin, Low-Molecular-Weight; 9005-49-6/Heparin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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